Carthage is one of the bigger towns you'll have seen. There is lots to see and do. We spent the night at the Boots Court Hotel. Even if you aren't staying in the town - it's well worth stopping past. For me it's one of the top hotels on the route. This is one of the true Route 66 "motels". Built in 1939 The "Motel" was saved from demolition by two sisters who are presently restoring the property to the way it was in 1949. With the five rooms in the detached annex being completed and opened for business in 2012.
Carthage has some nice buildings to look at as well with some antique places to have a rummage around.
Just past Carthage there is the 66 Drive in Theatre. 66 Drive-In is a historic drive-in theatre national historic district located on U.S. Route 66 in Carthage, Jasper County, Missouri. The theatre opened on September 22, 1949, four years before the first local television stations signed on in the Joplin-Springfield area. We didn't get a chance to watch a movie here (we did this later on in the route) but if you get a chance go see one!